Why be satisfied with snapshots if a comprehensive analysis of individual immune cells is within reach?
Massively parallel sequencing and spatial analysis approaches, such as single-cell immune profiling and single-cell transcriptomics, have enabled incredible advances in immunology and immunotherapy. Nevertheless, large gaps exist due to the limitations of whole-genome amplification (WGA) methods, which are required for single cell genomic analysis.
BioSkryb’s versatile and scalable single-cell whole genome amplification technology (PTA) and powerful bioinformatics platform (BaseJumper™) enable high-resolution analysis of genomic blueprints and functional gene expression profiles of individual immune cells. In combination with oligonucleotides and antibodies this offers the ability to study of each immune cell at the genomic, transcriptomic, and proteomic level.
In addition, our technology allows for the precision analysis of individual tumor cells. This uncovers clues about neo-antigen production and potential responses to checkpoint inhibitors, thereby assisting in the design of effective and personalized immunotherapies and disease management strategies.